Sandiso, a PhD student in pharmaceutical chemistry at Mandela University, and wants to address the pharmaceutical challenges facing the African continent, reducing South Africa’s dependence on costly imports from first-world countries.
Her cutting-edge research focuses on the synthesis of Coumarin compounds - key building blocks in the manufacturing of Active Pharmaceutical Ingredients (APIs). Coumarins, known for their bioactive properties, play a crucial role in preventing numerous diseases.
Through her innovative work with continuous flow chemistry, a novel and emerging technology in Africa, Sandiso wants to develop a cost-effective, high-yield method for synthesising these vital compounds.
Continuous flow chemistry, or micro-reaction technology (MRT), involves miniature-sized reactors that allow for uninterrupted chemical reactions in controlled systems.
This technique offers numerous advantages, such as shorter reaction times, better selectivity toward desired products, fewer by-products, and increased yields.
By integrating this synthetic protocol into the South African market, the local on-demand production will reduce imports.
Born and raised in Zimbabwe, she relocated to Zambia to complete her high school education due to the economic meltdown in Zimbabwe in 2008.
In 2014, Sandiso arrived in South Africa and graduated with a BSc in Chemistry and Chemical Science cum laude after three years. She then followed with a BSc Honours in Formulation Science and her master’s degree in chemistry, both with distinction. She then registered for her PhD in the same year, all at Mandela University.
However, Sandiso’s journey has not been without its challenges. Like many students, she has faced the daunting threat of imposter syndrome – a persistent feeling of inadequacy despite evident success.
Acknowledging the difficulty of silencing these inner voices, she sought support from student counselling services to assist her in navigating these mental and emotional hurdles. Her openness about this experience is an encouragement to others facing similar struggles.
Sandiso confronts ongoing challenges, but her commitment to her goals keeps her moving forward. She is driven to leave a meaningful mark on the world, and to honour her parents for the sacrifices they made to support her education.
Sandiso’s story is one of passion, resilience, and community support in overcoming obstacles and achieving greatness. As true scholar she is fuelled by curiosity and to effect positive change in the world. Her journey signifies the importance of representation in science and the powerful role that education and research play in shaping a brighter future for Africa.
CLICK TO WATCH THE VIDEO